Heart failure & cardiomyopathies

The intersection of obesity and acute heart failure: cardiac structure and function and congestion across body mass index (BMI) categories

Eur Heart J Acute Cardiovasc CarePublished Prospective cohort study

Authors' conclusion

Among patients with AHF, those with overweight/obesity had greater biventricular volumes/area and LV mass, similar sonographic evidence of haemodynamic congestion and less pulmonary congestion than those with normal weight. The risk of 6-month HF hospitalization or death was similar across BMI groups.

Study context

Population
Adults hospitalised for acute heart failure (HF), by BMI and left ventricular ejection fraction (LVEF) (>40% HFmrEF/HFpEF vs ≤40% HF with reduced EF (HFrEF))
Participants
354 adults
Exposure
Overweight and obese vs normal weight
Outcome
Cardiac structure and function and congestion across BMI groups
Follow-up
Baseline

Main finding

As reported in the abstract

Observational data: associations, not effects.

Further findings

HF hospitalisation or all-cause death · 6 months

Risk similar across BMI groups, overall and stratified by LVEF

Patient characteristics by BMI

Higher BMI: younger age, more comorbidities, more prior HF, worse patient-reported symptoms

Original publication

The intersection of obesity and acute heart failure: cardiac structure and function and congestion across BMI categories. Eur Heart J Acute Cardiovasc Care. Published 28 April 2025. doi:10.1093/ehjacc/zuaf067

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