Heart failure & cardiomyopathies

The Kinocardiograph for Assessment of Fluid Status in Patients with Acute Decompensated Heart Failure

ESC Heart FailPublished Proof-of-concept study

Authors' conclusion

KE measured with the KCG using SCG is highly responsive to changes in fluid status.

Study context

Population
Patients hospitalized with acute decompensated HF treated with IV diuretics
Participants
11 patients
Comparison
Kinetic energy (KE) by Kinocardiograph (KCG) before vs after diuretic treatment
Outcome
Responsiveness of cardiac kinetic energy (KE) measured with the Kinocardiograph during treatment
Follow-up
Daily until discharge

Main finding

As reported in the abstract

Median KE (IQR), admission to discharge
GroupPassive filling phaseActive filling phasePassive/active ratio
Seismocardiographic (SCG)0.48 (0.39-0.60) to 0.69 (0.56-0.84), P = 0.0260.38 (0.30-0.61) to 0.31 (0.09-0.47), P = 0.0162.76 (1.68-5.30) to 5.02 (3.13-10.17), P = 0.006
Ballistocardiographic (BCG)0.68 (0.46-0.73) to 0.68 (0.59-0.82), P = 0.0620.29 (0.17-0.39) to 0.26 (0.20-0.34), P = 0.2485.87 (3.57-7.55) to 5.27 (3.95-9.43), P = 0.790

Passive filling phase

Seismocardiographic (SCG)0.48 (0.39-0.60) to 0.69 (0.56-0.84), P = 0.026
Ballistocardiographic (BCG)0.68 (0.46-0.73) to 0.68 (0.59-0.82), P = 0.062

Active filling phase

Seismocardiographic (SCG)0.38 (0.30-0.61) to 0.31 (0.09-0.47), P = 0.016
Ballistocardiographic (BCG)0.29 (0.17-0.39) to 0.26 (0.20-0.34), P = 0.248

Passive/active ratio

Seismocardiographic (SCG)2.76 (1.68-5.30) to 5.02 (3.13-10.17), P = 0.006
Ballistocardiographic (BCG)5.87 (3.57-7.55) to 5.27 (3.95-9.43), P = 0.790

Further findings

Weight and inferior vena cava (IVC) diameter after diuretic treatment

Median weight (IQR), kg
74.5 (67.6-98.7) to 73.3 (66.7-95.6), P = 0.003
Median IVC diameter (IQR), cm
2.47 (2.33-2.99) to 1.78 (1.65-2.47), P = 0.03

Correlation of SCG KE changes with weight or IVC changes

Non-significant correlations

Original publication

The Kinocardiograph for Assessment of Fluid Status in Patients with Acute Decompensated Heart Failure. ESC Heart Fail. Published 14 September 2023. doi:10.1002/ehf2.14477

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