Valvular & structural heart diseaseCohort study
The Relevance of Right Ventricular Function and Dimension in Patients Undergoing Transcatheter Tricuspid Edge-to-Edge Repair
- Registry-based cohort study
- multicentre
- international registry (EuroTR)
- 20 centres across Europe
Authors' conclusion
RV size and function, along with residual TR severity, were significant predictors of clinical outcomes, including all-cause mortality and heart failure hospitalization.
Study context
- Population
- Patients with severe tricuspid regurgitation (TR) undergoing transcatheter tricuspid edge-to-edge repair (T-TEER) in the EuroTR registry, 2016–2023
- Participants
- 2,191 patients
- Exposure
- Right ventricular (RV) dysfunction and dilation vs normal RV function and dimension
- Outcome
- All-cause mortality
Main finding
As reported in the abstract
Predictors of mortality after T-TEER (multivariable)
Hazard ratio (95% CI)
RV dysfunctionper 1-mm TAPSE decrease
1.05(1.03–1.08)
RV dilationper 1-mm RV mid-diameter increase
1.02(1.00–1.03)
Residual TR after T-TEERfor TR grade ≤2
1.70(1.36–2.13)
Each row per its own increment, as printed
Observational data: associations, not effects.
Further findings
TR reduced to ≤2+
- TR reduced to ≤2+
- 80% (1,608 of 2,001)
Mortality and HF hospitalization (combined)
- RV dysfunction, RV dilation and residual TR also predictive
Original publication
The Relevance of Right Ventricular Function and Dimension in Patients Undergoing Transcatheter Tricuspid Edge-to-Edge Repair. JACC Cardiovasc Interv. Published 28 July 2025. doi:10.1016/j.jcin.2025.05.037
Summarised from the published abstract; every number is checked against it