Heart failure & cardiomyopathies

The Role of Intra-Abdominal Pressure and Point of Care Ultrasound to Guide Decongestive Therapies in Acute Heart Failure

ESC Heart FailPublished randomized, multicentre, open-label, pragmatic clinical trial

Authors' conclusion

The ABDOPOCUS-HF trial investigates whether integrating IAP and POCUS into decongestion strategies improves diuretic response and clinical outcomes in ADHF patients. Findings may inform future protocols for volume management in acute heart failure.

Study context

Population
Patients hospitalized with acute decompensated heart failure (ADHF) with clinical signs of congestion and elevated natriuretic peptides (NT-proBNP >1000 pg/mL or BNP > 250 pg/mL)patients hospitalized with ADHF across 14 Spanish hospitals
Participants
168 patients
Comparison
a strategy guided by intra-abdominal pressure (IAP) and point-of-care ultrasound (POCUS) compared to standard diuretic titration
Primary endpoint
resolution of systemic congestion, measured by the ADVOR score
Follow-up
72 h
Methodological details14 Spanish hospitals, 1:1 randomization
  • 14 Spanish hospitals
  • 1:1 randomization

Original publication

The Role of Intra-Abdominal Pressure and Point of Care Ultrasound to Guide Decongestive Therapies in Acute Heart Failure. ESC Heart Fail. Published 30 July 2025. doi:10.1002/ehf2.15380

Summarised from the published abstract; every number is checked against it

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