Prevention & lipidsCohort study
The Southern European Atlantic diet and all-cause and cause-specific mortality: a European multicohort study
- Prospective cohort study
- multicohort
- pooled analysis of four cohorts
Authors' conclusion
The SEAD was associated with lower all-cause, cardiovascular, and cancer mortality in southern, central, eastern, and western European populations.
Study context
- Population
- Adults aged 18–96 years in four European cohorts: ENRICA (Spain), HAPIEE (Czechia and Poland), Whitehall II (UK)
- Participants
- 35,917 adults · 4 cohorts
- Exposure
- Higher vs lower adherence to the Southern European Atlantic diet
- Outcome
- All-cause, CV and cancer mortality
- Follow-up
- Median 13.6 years (range = 0-15)
Main finding
As reported in the abstract
All-cause, CV and cancer mortality (pooled sample) · median follow-up 13.6 years
SEADHazard ratio (95% CI)
all-cause mortality, per 1-SD increment, fully adjusted
0.92(0.89–0.95)
CV mortality, per 1-SD increment, fully adjusted
0.91(0.86–0.96)
cancer mortality, per 1-SD increment, fully adjusted
0.94(0.89–0.99)
Per 1-SD increment, as printed
Observational data: associations, not effects.
Further findings
All-cause mortality, by country (subgroup)
| Comparison | HR (CI) | |
|---|---|---|
| SEAD · Spain | 0.93 (0.88–0.99) | |
| SEAD · Czechia | 0.94 (0.89,0.99) | |
| SEAD · Poland | 0.89 (0.85–0.93) | |
| SEAD · United Kingdom | 0.98 (0.89–1.07) | |
| 0.512Hazard ratio (log scale) |
- All-cause mortality, by country (subgroup): P for interaction = 0.16
All-cause mortality, by country (subgroup)
- Association not significantly different between countries
Original publication
The Southern European Atlantic diet and all-cause and cause-specific mortality: a European multicohort study. Eur J Prev Cardiol. Published 15 December 2023. doi:10.1093/eurjpc/zwad370
Summarised from the published abstract; every number is checked against it