Arrhythmias & electrophysiology

The Value of Functional Fascicular Block in Patients With Atrioventricular Re-Entrant Tachycardia

JACC Clin ElectrophysiolPublished Observational electrophysiological study

Authors' conclusion

In patients with AVRT, ΔVAI during complete BBB enables more robust AP localization compared with incomplete BBB. Moreover, ΔVAI during FB allows for AP localization along the mitral annulus, especially LAFB for left lateral APs and LPFB for posterior-septal and left posterior APs.

Study context

Population
Patients with AVRT and single non-decremental accessory pathway (APs) (left free wall, septal, right free wall) displaying functional fascicular block (FB) or bundle branch block (BBB) during AVRT
Participants
419 single non-decremental APs
Exposure
ΔVAI during functional FB vs BBB by AP location
  • Left free walln = 207
  • Septaln = 159
  • Right free walln = 53
Outcome
Change in ventriculoatrial interval (ΔVAI) by AP location

Main finding

As reported in the abstract

ΔVAI by AP location
  • Left and right free wall APs: ΔVAI increased with ipsilateral BBB
  • Complete BBB distinguished AP location better than incomplete BBB
  • LAFB: ΔVAI prolongation with left lateral and posterior-lateral APs; no ΔVAI with left posterior and posterior-septal APs
  • LPFB: marked ΔVAI lengthening with left posterior, posterior-lateral and posterior-septal APs; no ΔVAI with left lateral APs

Observational data: associations, not effects.

Original publication

The Value of Functional Fascicular Block in Patients With Atrioventricular Re-Entrant Tachycardia. JACC Clin Electrophysiol. Published 6 August 2025. doi:10.1016/j.jacep.2025.06.006

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