Arrhythmias & electrophysiology

Traditional and HIV-Specific Risk Factors Associated With Atrial Fibrillation Among Underrepresented Minority Groups With HIV

JACC AdvPublished Secondary analysis of the PATHWAYS retrospective population-based study

Authors' conclusion

In this cohort of UREGs living with HIV, both traditional and HIV-specific risk factors were associated with incident NVAF. Rates of appropriate OAC prescribing were low.

Study context

Population
Under-represented racial and ethnic minority groups (UREGs) living with HIV, 2015–201910,945 without NVAF at baseline
Participants
11,066 participants
Primary endpoint
Incidence of NVAF (nonvalvular AF/atrial flutter) and associated factors
Methodological detailsCox regression
  • Cox regression

Primary result

As reported in the abstract

Incident NVAF · average follow-up 3.4 years

Incidence of NVAF

4.54 incident cases per 1,000 person-years

Cumulative incidence 1 year after HIV diagnosis

0.48%

Cumulative incidence 5 years after HIV diagnosis

2.16%

Further findings

Any oral anticoagulation (OAC) prescription for stroke prophylaxis among those with NVAF meeting qualifying CHA2DS2-VASc scores

Received any OAC prescription
44.2%

Original publication

Traditional and HIV-Specific Risk Factors Associated With Atrial Fibrillation Among Underrepresented Minority Groups With HIV. JACC Adv. Published 27 October 2025. doi:10.1016/j.jacadv.2025.102287

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