Coronary disease & ACS

Transcoronary cooling and dilution for cardioprotection during revascularisation for ST-segment elevation myocardial infarction: Design and rationale of the STEMI-Cool study

Am Heart JPublished Design and rationale of a randomised pilot trial

An erratum to this article was published (Am Heart J, Oct 2025 ↗)

Study context

Population
STEMI patients undergoing primary PCIplanned, 1:1 randomisation
Participants
60 patients
Planned comparison
Transcoronary cooling and dilution vs standard of care during primary percutaneous coronary intervention (pPCI)
Primary endpoint
Recruitment rate, feasibility and safety of the cooling and dilution protocol
Methodological detailspragmatic, registry-based
  • Pragmatic
  • Registry-based

No results yet. This paper sets out the design of a trial; its results are to come.

Original publication

Transcoronary cooling and dilution for cardioprotection during revascularisation for ST-segment elevation myocardial infarction: Design and rationale of the STEMI-Cool study. Am Heart J. Published 30 December 2024. doi:10.1016/j.ahj.2024.12.009

Summarised from the published abstract; every number is checked against it

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