Ultrasound guidance for transfemoral access in coronary procedures: an individual participant-level data metaanalysis from the femoral ultrasound trialist collaboration
Pooled resultResult — go to the resultOdds ratio 0.61 95% CI 0.39–0.94Authors' conclusion
In participants undergoing coronary procedures by TFA, US guidance decreased the composite outcome of major vascular complications or bleeding and may be especially helpful when using vascular closure devices.
Study context
- Population
- Participants undergoing coronary procedures by transfemoral access; mean age 65.5 years, 27.0% female, 34.5% underwent PCI
- Participants
- 2,441 participants4 RCTs
- Comparison
- Ultrasound (US)-guided vs non-US-guided transfemoral access
- US-guidedn = 1,208
- non-US-guidedn = 1,233reference
- Outcome
- Composite of:
- Major vascular complications
- Major bleeding
- Follow-up
- Within 30 days
Methodological detailsone-stage mixed-model meta-analysis, intention-to-treat
- One-stage mixed-model meta-analysis
- Intention-to-treat
Pooled result
As reported in the abstract
Odds ratio
0.61
95% CI 0.39–0.94
P = 0.026
Events by group
US-guidedvs non-US-guided
OR 0.61 (95% CI 0.39–0.94); P = 0.026
Further pooled results
| Outcome | US-guided | non-US-guided | OR (95% CI) | |
|---|---|---|---|---|
| Primary outcome, by vascular closure device use (prespecified subgroup)With vascular closure device | 2.1% | 5.6% | 0.36 (0.19–0.69) | |
| Primary outcome, by vascular closure device use (prespecified subgroup)Without vascular closure device | 4.1% | 3.3% | 1.21 (0.65–2.26) | |
| 0.20.5125Odds ratio (log scale) |
- Primary outcome, by vascular closure device use (prespecified subgroup): interaction p=0.009
Original publication
Ultrasound guidance for transfemoral access in coronary procedures: an individual participant-level data metaanalysis from the femoral ultrasound trialist collaboration. EuroIntervention. Published 1 January 2024. doi:10.
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