Heart failure & cardiomyopathies
Ultrasound shear wave elastography for detection of myocardial fibrosis
Authors' conclusion
Natural SWVs can distinguish between normal and pathological myocardium and depend on the fibrosis burden of the myocardium.
Study context
- Population
- Heart transplanted patients and hypertrophic cardiomyopathy patients, and healthy volunteersplus 37 healthy volunteers · heart transplanted patients 30 · hypertrophic cardiomyopathy patients 22 · healthy volunteers 37
- Participants
- Fifty-two patients participants
- Comparison
- Shear wave (SW) velocities vs classification by T1 mapping, extracellular volume (ECV) mapping and late gadolinium enhancement measured by cardiac magnetic resonance
- Outcome
- SWVs among groups
Methodological detailsexperimental scanner at 1172 ± 302 frames per second
- Experimental scanner at 1172 ± 302 frames per second
Performance
As reported in the abstract
- SW velocities (SWVs) differed among groups
- P < 0.001
Further findings
Correlation of SWVs with ECV values
- R
- 0.70
- P
- P < 0.0001
Correlation of SWVs with native T1 values
- R
- 0.48
- P
- P = 0.0004
SWVs below 6.0 m/s to identify patients without fibrosis
- Sensitivity
- 90%
- Specificity
- 90%
- AUC
- 0.95
Cut-off of 8.1 m/s to distinguish MRF from MIF
- Sensitivity
- 69%
- Specificity
- 100%
- AUC
- 0.92
Original publication
Ultrasound shear wave elastography for detection of myocardial fibrosis. Eur Heart J Cardiovasc Imaging. Published 10 July 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →