Valvular & structural heart disease
UNICORN During Transcatheter Aortic Valve Replacement in Native and Bioprosthetic Aortic Valves: A Multicenter Study
Authors' conclusion
UNICORN during TAVR was successful in preventing coronary obstruction. Intraprocedural hypotension requiring vasopressor support was frequent.
Study context
- Population
- Patients undergoing UNICORN transcatheter aortic valve replacement (TAVR) in native, surgical or transcatheter aortic valves, March 2024 to May 20258 native, 30 surgical, 15 TAVR valves
- Participants
- 53 patients
- Outcome
- Primary success: UNICORN TAVR without periprocedural coronary obstruction, reintervention or death
Methodological details9 sites, consecutive patients
- 9 sites
- Consecutive patients
Main finding
As reported in the abstract
Primary success (UNICORN TAVR without periprocedural coronary obstruction, reintervention or death)
Primary success
51 patients
96%
Observational data: associations, not effects.
Further findings
Coronary obstruction requiring rescue PCI
- Coronary obstruction with rescue PCI
- 2 (4%)
Safety
Overall 30-day safety
- Overall 30-day safety
- 46 patients (87%)
- Stroke
- 3 (6%)
- Life-threatening bleeding
- 2 (4%)
- Major vascular complications
- 2 (4%)
- Deaths, valve-related reinterventions, stage 3–4 AKI
- 0
Intraprocedural hypotension
- Intraprocedural hypotension
- 12 (23%)
Original publication
UNICORN During Transcatheter Aortic Valve Replacement in Native and Bioprosthetic Aortic Valves: A Multicenter Study. JACC Cardiovasc Interv. Published 22 June 2026. doi:10.
Summarised from the published abstract; every number is checked against it