Heart failure & cardiomyopathies
The Use of Left Ventricular Ejection Fraction in the Diagnosis and Management of Heart Failure. A Clinical Consensus Statement of the Heart Failure Association (HFA) of the ESC, the Heart Failure Society of America (HFSA), and the Japanese Heart Failure Society (JHFS)
Recommendations
As issued by the authors
Left ventricular ejection fraction (LVEF) reproducibility is poor; its prognostic and diagnostic value lessens above 45%, with no relationship to severity of cardiac dysfunction or outcomes at higher values
A more comprehensive approach to classify and assess HF is needed, focusing on the trajectory of LVEF rather than its absolute value
LVEF assessment is not required to initiate SGLT2 inhibitors, MRAs and diuretics in suspected de novo HF with elevated NT-proBNP
Original publication
The Use of Left Ventricular Ejection Fraction in the Diagnosis and Management of Heart Failure. A Clinical Consensus Statement of the Heart Failure Association (HFA) of the ESC, the Heart Failure Society of America (HFSA), and the Japanese Heart Failure Society (JHFS). Eur J Heart Fail. Published 22 April 2025. doi:10.
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