Heart failure & cardiomyopathies

Factors associated with NT-proBNP concentration in US children and adolescents: National Health and Nutrition Examination Survey 1999-2004

Am Heart JPublished cross-sectional analysis

Authors' conclusion

The differences in NT-proBNP by age, sex, and race or ethnicity in younger persons mirror those seen in adults. These results suggest that as in adults, levels of NT-proBNP should be interpreted in children and adolescents based on these demographic and clinical factors.

Study context

Population
Youth ages <20 years old in the National Health and Nutrition Examination Survey 1999 to 2004
Exposure
Associations between NT-proBNP and cardiometabolic risk factors
Outcome
Association of NT-proBNP with BMI and cardiometabolic risk factors
Methodological detailsnationally representative
  • Nationally representative

Main finding

As reported in the abstract

  • NT-proBNP was inversely associated with BMI and most cardiometabolic risk factors

Observational data: associations, not effects.

Original publication

Factors associated with NT-proBNP concentration in US children and adolescents: National Health and Nutrition Examination Survey 1999-2004. Am Heart J. Published 22 April 2025. doi:10.1016/j.ahj.2025.04.011

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