Heart failure & cardiomyopathies
Value of 3D echocardiography in the diagnosis of arrhythmogenic right ventricular cardiomyopathy
Authors' conclusion
The combination of 2DE-3DE for ARVC diagnosis is comparable to the conventional 2DE-cMRI approach.
Study context
- Population
- Individuals (47±15 years) with suspected arrhythmogenic right ventricular cardiomyopathy (ARVC)
- Participants
- 39 individuals
- Comparison
- 2DE-3DE vs 2DE-cMRI for ARVC diagnosis by 2010 Task Force Criteria (TFC)
- Outcome
- Concordance of ARVC diagnosis by 2010 TFC between 2DE-3DE and 2DE-cMRI (kappa)
Methodological detailsblinded classification, non-inferiority
- Blinded classification
- Non-inferiority
Performance
As reported in the abstract
ARVC diagnosis by 2010 TFC (concordance between approaches)
| Test or model | Not affected | Possible | Borderline | Definite |
|---|---|---|---|---|
| 2DE-cMRI | 3/39 | 5/39 | 8/39 | 23/39 |
| 2DE-3DE | 5/39 | 7/39 | 8/39 | 19/39 |
Not affected
2DE-cMRI3/39
2DE-3DE5/39
Possible
2DE-cMRI5/39
2DE-3DE7/39
Borderline
2DE-cMRI8/39
2DE-3DE8/39
Definite
2DE-cMRI23/39
2DE-3DE19/39
Further findings
| Outcome | 3DE | 2DE | cMRI |
|---|---|---|---|
| Detection of RV WMA | 28/39 | 11/39 | 33/39 |
Right ventricular (RV) volumes, 3DE vs cardiovascular magnetic resonance imaging (cMRI)
- 3DE underestimated RV volumes vs cMRI, in some instances interfering with fulfilment of a major criterion
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Value of 3D echocardiography in the diagnosis of arrhythmogenic right ventricular cardiomyopathy. Eur Heart J Cardiovasc Imaging. Published 3 September 2022. doi:10. 1093/ ehjci/ jeac172
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