Valvular & structural heart disease

Variation in resource utilization and mortality among patients with varying mitral regurgitation (MR) type and severity

Am Heart JPublished Retrospective cohort study

Authors' conclusion

Resource utilization and outcomes vary by MR type and severity. Utilization of resources, such as TTE, during guideline-recommended surveillance periods was not associated with a reduction in mortality while other care (catheterization or surgery) was associated with improved survival.

Study context

Population
Patients with moderate or severe MR on index echo, Duke Echocardiography Laboratory Database, 2000–201684.7% moderate MR
Participants
4,511 patients
Exposure
Resource utilization and outcomes across MR type and severity
Outcome
Cumulative resource utilization (TTE, TEE, cardiac catheterization, cardiology/CTS referral, MV surgery/TEER, hospitalizations) by MR severity and type; 5-year mortality
Follow-up
5 years
Methodological detailssingle-centre echocardiography database, multivariable landmark analysis
  • Single-centre echocardiography database
  • Multivariable landmark analysis

Main finding

As reported in the abstract

Resource utilization
Mean 5-year cumulative resource utilization rate (encounters/patient)
11.1
Significant variation in utilization of each resource by MR type
all P < .05

Observational data: associations, not effects.

Further findings

5-year mortality by resource use during landmark period (6 to 12 months)

Moderate MR: CTS referral associated with significantly lower mortality
P < 0.05
Severe MR: cardiac catheterization or MV surgery associated with significantly lower mortality

5-year hospitalization costs by MR type

Secondary ischemic and non-ischemic MR had significantly higher costs vs primary myxomatous MR
P < 0.05

Original publication

Variation in resource utilization and mortality among patients with varying MR type and severity. Am Heart J. Published 13 February 2023. doi:10.1016/j.ahj.2023.01.005

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