Valvular & structural heart disease
Health Care Cost and Resource Utilization After Aortic Valve Replacement According to the Extent of Cardiac Damage
Authors' conclusion
Among patients undergoing AVR for aortic stenosis, the extent of cardiac damage before AVR was independently associated with increased costs and health care resource utilization during the index AVR admission and through 1 year post-AVR.
Study context
- Population
- Patients with aortic stenosis treated with aortic valve replacement (AVR) between 2016 and 2022, Optum de-identified Market Clarity databasepatients with AVR
- Participants
- 24,644 patients
- Exposure
- Stages 1-4 of cardiac damage compared with stage 0
- Outcome
- Distribution across stages of cardiac damage
Methodological detailscovariate-adjusted generalized linear models
- Covariate-adjusted generalized linear models
Main finding
As reported in the abstract
Observational data: associations, not effects.
Further findings
| Outcome | Difference | P value |
|---|---|---|
| Total costs · AVR hospitalization and the following yearStage 1 vs stage 0 · increased | $2746 | P < 0.01 |
| Total costs · AVR hospitalization and the following yearStage 2 vs stage 0 · increased | $19 511 | P < 0.01 |
| Total costs · AVR hospitalization and the following yearStage 3 vs stage 0 · increased | $19 198 | P < 0.01 |
| Total costs · AVR hospitalization and the following yearStage 4 vs stage 0 · increased | $35 663 | P < 0.01 |
Length of stay, all-cause and heart failure hospitalizations, all-cause and heart failure days in-hospital
- Significantly increased with the extent of cardiac damage
Cost and resource utilization, risk-adjusted
- Advanced stages of cardiac damage associated with both higher cost and resource utilization compared with stage 0
- Risk-adjusted models
Original publication
Health Care Cost and Resource Utilization After Aortic Valve Replacement According to the Extent of Cardiac Damage. Circ Cardiovasc Interv. Published 7 April 2025. doi:10. 1161/ circinterventions. 124. 014945
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