Valvular & structural heart disease

Health Care Cost and Resource Utilization After Aortic Valve Replacement According to the Extent of Cardiac Damage

Circ Cardiovasc IntervPublished Retrospective cohort study

Authors' conclusion

Among patients undergoing AVR for aortic stenosis, the extent of cardiac damage before AVR was independently associated with increased costs and health care resource utilization during the index AVR admission and through 1 year post-AVR.

Study context

Population
Patients with aortic stenosis treated with aortic valve replacement (AVR) between 2016 and 2022, Optum de-identified Market Clarity databasepatients with AVR
Participants
24,644 patients
Exposure
Stages 1-4 of cardiac damage compared with stage 0
Outcome
Distribution across stages of cardiac damage
Methodological detailscovariate-adjusted generalized linear models
  • Covariate-adjusted generalized linear models

Main finding

As reported in the abstract

Observational data: associations, not effects.

Further findings

OutcomeDifferenceP value
Total costs · AVR hospitalization and the following yearStage 1 vs stage 0 · increased$2746P < 0.01
Total costs · AVR hospitalization and the following yearStage 2 vs stage 0 · increased$19 511P < 0.01
Total costs · AVR hospitalization and the following yearStage 3 vs stage 0 · increased$19 198P < 0.01
Total costs · AVR hospitalization and the following yearStage 4 vs stage 0 · increased$35 663P < 0.01

Length of stay, all-cause and heart failure hospitalizations, all-cause and heart failure days in-hospital

Significantly increased with the extent of cardiac damage

Cost and resource utilization, risk-adjusted

Advanced stages of cardiac damage associated with both higher cost and resource utilization compared with stage 0
  • Risk-adjusted models

Original publication

Health Care Cost and Resource Utilization After Aortic Valve Replacement According to the Extent of Cardiac Damage. Circ Cardiovasc Interv. Published 7 April 2025. doi:10.1161/circinterventions.124.014945

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