Arrhythmias & electrophysiology
Ventricular Intramyocardial Navigation for Tachycardia Ablation Guided by Electrograms (VINTAGE)): Initial Human Experience
Authors' conclusion
VINTAGE was effective at creating intramural ablation lesions and treating ventricular arrhythmias arising from targets traditionally considered inaccessible from the endocardium and epicardium, including infarcted myocardium.
Study context
- Population
- Patients with recurrent ventricular tachycardia (VT) or high premature ventricular contractions (PVC) burden despite prior ablation and antiarrhythmic drugs
- Participants
- 13 patients14 procedures
- Outcome
- Clinical success by patient (reduction in VT therapy or PVC burden >80%)
- Follow-up
- Median 150 days
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
Clinical success, all patients
85%
Clinical success, VT
100%
Clinical success, PVC
75%
Observational data: associations, not effects.
Further findings
Freedom from appropriate ICD shocks, appropriate antitachycardia pacing or hospital admission for recurrent VT (VT cohort)
- Free from appropriate ICD shocks, ATP or VT admission
- 4 of 5 (80%)
Technical success
- Technical success
- 100%
Safety
| Outcome | Values |
|---|---|
| Complications | VINTAGE Nondisabling stroke 1 · Vascular complication 1 |
Original publication
Ventricular Intramyocardial Navigation for Tachycardia Ablation Guided by Electrograms (VINTAGE)): Initial Human Experience. JACC Clin Electrophysiol. Published 23 July 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →