Arrhythmias & electrophysiology
Very High-Power Ablation for Contiguous Pulmonary Vein Isolation: Results From the Randomized POWER PLUS Trial
Authors' conclusion
Contiguous ablation using very high-power, short-duration applications results in a significant but modest reduction in procedure time with similar safety and 6-month efficacy vs a conventional approach.
Study context
- Population
- Patients with paroxysmal or persistent AF undergoing first-time pulmonary vein isolation (PVI)
- Participants
- 180 patients
- Comparison
- Very high-power, short-duration ablation vs 35/50-W ablation for PVI
- 90-Wn = 90
- 35/50-Wn = 90reference
- Primary endpoint
- Procedural efficiency (procedure time and first-pass isolation), safety (incl. esophageal endoscopic evaluation) and 6-month effectiveness (repetitive Holter monitoring)
Methodological detailsmulticentre
- Multicentre
Primary result
As reported in the abstract
Procedure time
P = 0.009
Further findings
First-pass isolation · nonsignificant trend
P = 0.0852
Recurrent arrhythmia · 6 months
P = 0.681
Safety
Events
| Outcome | 90-W | 35/50-W |
|---|---|---|
| Major complications | 0 | 0 |
| Esophageal injury | 1 | 1 |
Original publication
Very High-Power Ablation for Contiguous Pulmonary Vein Isolation: Results From the Randomized POWER PLUS Trial. JACC Clin Electrophysiol. Published 18 January 2023. doi:10.
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