Heart failure & cardiomyopathies
Waitlist Outcomes in Candidates With Rare Causes of Heart Failure After Implementation of the 2018 French Heart Allocation Scheme
Authors' conclusion
Our study shows equitable waitlist outcomes among HT candidates whatever the indication for transplantation with the new French allocation scheme.
Study context
- Population
- Adults listed for heart transplantation in France, 2018–2020, after the 2018 algorithm-based allocation scheme
- Participants
- 1,604 adults
- Exposure
- Rare causes of heart failure (HF) vs other cardiomyopathies
- Outcome
- Death on the waitlist or delisting for clinical deterioration
- Follow-up
- 1 year postlisting
Methodological detailsnational
- National
Main finding
As reported in the abstract
Each group vs other cardiomyopathiesSubdistribution hazard ratio (95% CI)P value
Hypertrophic cardiomyopathy
0.51(0.19–1.38)
P = 0.18RCM
1.04(0.42–2.58)
P = 0.94Congenital heart disease
1.82(0.78–4.26)
P = 0.17- Patients meeting the primary end point (overall)
- 175
- Cumulative incidence of death on the waitlist similar between diagnosis groups
- P = 0.17
Observational data: associations, not effects.
Secondary outcomes
| Outcome | HR (95% CI) | P value | |
|---|---|---|---|
| Access to HTHypertrophic cardiomyopathyvs Other cardiomyopathies | 1.18 (0.92–1.51) | P = 0.19 | |
| Access to HTRCMvs Other cardiomyopathies | 1.19 (0.90–1.58) | P = 0.23 | |
| Access to HTCongenital heart diseasevs Other cardiomyopathies | 0.76 (0.53–1.09) | P = 0.14 | |
| Posttransplant mortality · 1 yearRCMvs Other cardiomyopathiesIndependent risk factor | 2.12 (1.06–4.24) | P = 0.03 | |
| 0.20.5125Hazard ratio (log scale) |
Score exceptions
- Access to heart transplantation (HT) — Underwent HT at 1 year (overall)
- 1040
- Access to HT — Probability of HT similar between diagnosis groups
- 0.40
Original publication
Waitlist Outcomes in Candidates With Rare Causes of Heart Failure After Implementation of the 2018 French Heart Allocation Scheme. Circ Heart Fail. Published 1 February 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →