“Weekend Warrior” Physical Activity and Adipose Tissue Deposition
Authors' conclusion
Guideline-adherent physical activity is associated with favorable quantitative measures of cardiometabolic health, with no differences based on activity pattern for a given activity volume.
Study context
- Population
- UK Biobank participants who wore accelerometers for 1 week and later underwent cardiac magnetic resonance imagingUK Biobank participants analyzed
- Participants
- 17,146 participants
- Exposure
- Weekend warrior and regular activity compared to inactive, and weekend warriors compared directly with regular activity
- Outcome
- VAT
Methodological detailsUK Biobank, accelerometers worn for 1 week, cardiac magnetic resonance imaging, multiple linear regression adjusted for confounding factors
- UK Biobank
- Accelerometers worn for 1 week
- Cardiac magnetic resonance imaging
- Multiple linear regression adjusted for confounding factors
Main finding
As reported in the abstract
Difference, L (95% CI)P value
Weekend warriorvs inactive
−0.71(−0.78 to −0.64)
P < 0.001Regularvs inactivelower with regular activity
−0.96(−1.04 to −0.88)
P < 0.001Observational data: associations, not effects.
Further findings
| Outcome | Estimate | P value | |
|---|---|---|---|
| EPATWeekend warriorvs inactive | difference −2.84 cm² (95% CI −3.20 to −2.49) | P < 0.001 | |
| EPATRegularvs inactiveLower with regular activity | difference −3.62 cm² (95% CI −4.03 to −3.20) | P < 0.001 | |
| VAT and EPAT, weekend warrior compared directly with regular activityWeekend warriorvs regular | EPAT difference 0.78 cm² (95% CI 0.40–1.15) | P < 0.001 | |
| VAT and EPAT, weekend warrior vs regular, after adjustment for total moderate-to-vigorous physical activity minutesWeekend warriorvs regular | EPAT difference 0.04 cm² (95% CI −0.35 to 0.43) | P = 0.84 | |
| −6−4−202Difference, cm² (linear scale) |
| Outcome | VAT difference (L) (95% CI) | P value | |
|---|---|---|---|
| VAT and EPAT, weekend warrior compared directly with regular activityWeekend warriorvs regular | 0.25 (0.17–0.32) | P < 0.001 | |
| VAT and EPAT, weekend warrior vs regular, after adjustment for total moderate-to-vigorous physical activity minutesWeekend warriorvs regular | 0.07 (−0.01 to 0.14) | P = 0.09 | |
| −0.200.20.4Difference, L (linear scale) |
- Visceral adipose tissue (VAT) and epicardial and pericardial adipose tissue (EPAT), weekend warrior vs regular, after adjustment for total moderate-to-vigorous physical activity minutes: positive estimate: higher with weekend warrior; no difference observed
- VAT and EPAT, weekend warrior vs regular, after adjustment for total moderate-to-vigorous physical activity minutes: positive estimate: higher with weekend warrior; no difference observed
- VAT and EPAT, weekend warrior vs regular, after adjustment for total moderate-to-vigorous physical activity minutes: adjusted for total moderate-to-vigorous physical activity minutes
VAT and EPAT, weekend warrior vs regular, after adjustment for total moderate-to-vigorous physical activity minutes
- No differences were observed
Original publication
“Weekend Warrior” Physical Activity and Adipose Tissue Deposition. JACC Adv. Published 15 February 2025. doi:10.
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