Valvular & structural heart disease
1-Year Outcomes of Transcatheter Tricuspid Valve Repair
Authors' conclusion
The PASCAL system demonstrated low complication and high survival rates, with significant and sustained improvements in TR, functional status, and quality of life at 1 year.
Study context
- Population
- Patients with severe or greater tricuspid regurgitation (TR) and persistent symptoms despite medical treatmentmean age 77.4 y
- Participants
- 65 patients
- Outcome
- Primary safety and performance outcomes; 1-year all-cause mortality and HF hospitalization
- Follow-up
- 1 year
Methodological detailsmulticentre, independent core laboratory, clinical events committee
- Multicentre
- Independent core laboratory
- Clinical events committee
Main finding
As reported in the abstract
Freedom from all-cause mortality and HF hospitalisation (Kaplan-Meier)
Freedom from all-cause mortality (Kaplan-Meier)
87.9%
Freedom from HF hospitalisation (Kaplan-Meier)
78.5%
Observational data: associations, not effects.
Further findings
CV mortality, stroke and device-related reintervention · 30 days
- CV mortality
- 3.1%
- Stroke
- 1.5%
- No device-related reinterventions
CV deaths, strokes and unplanned or emergency reintervention · Between 30 days and 1 year
- Additional CV deaths: 3
- 4.8%
- Strokes: 2
- 3.2%
- Unplanned or emergency reintervention: 1
- 1.6%
TR severity · 1 year
- TR severity significantly reduced
- P < 0.001
- Moderate or less TR: 31 of 36
- 86.0%
- At least 1 TR grade reduction
- 100%
NYHA class, 6-minute walk distance, KCCQ · 1 year
- NYHA class significantly improved
- P < 0.001
- NYHA class I or II
- 92%
- 6-minute walk distance increased by 94 m
- P = 0.014
- KCCQ overall score improved by 18 points
- P < 0.001
Original publication
1-Year Outcomes of Transcatheter Tricuspid Valve Repair. J Am Coll Cardiol. Published 9 May 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →