Coronary disease & ACSCohort study
A family-based strategy to identify and prevent premature cardiovascular disease: a feasibility pilot study
- Feasibility pilot study
- prospective
Authors' conclusion
This pilot study revealed (i) a significant familial burden of CVD, (ii) opportunities for proactive primary prevention in two out of three of young relatives, and (iii) challenges in engaging non-symptomatic adults in a cardiovascular screening based on family history.
Study context
- Population
- First-degree relatives of patients with premature coronary artery disease (CAD)
- Participants
- 137 probands
- Outcome
- Eligibility of relatives for initial CV evaluation (no previously known CVD or active primary prevention)
Main finding
As reported in the abstract
Siblings and adult children eligible for initial CV check-up (n=352)
226 (64.2%)
Siblings and adult children already diagnosed with cardiovascular disease (CVD)
48 (13.7%)
Siblings and adult children treated or followed for primary prevention
68 (19.3%)
Observational data: associations, not effects.
Further findings
Known CVD among first-degree relatives
- Relatives with known CVD (of 626)
- 153 (24.4%)
- Relatives with known CAD
- 19.6%
Eligible relatives initiating screening · within 12 months
- Eligible relatives who initiated screening
- 11.1%
Original publication
Summarised from the published abstract; every number is checked against it