Arrhythmias & electrophysiology

Active Arrhythmia Pattern: A Novel Predictor of Implantable Cardioverter Defibrillator (ICD) Shocks—A Subanalysis From the PARTITA Study

Circ Arrhythm ElectrophysiolPublished Secondary analysis of the PARTITA trial

Authors' conclusion

Patients with an active arrhythmia pattern (≥5 ATPs in 6 months) are associated with an increased risk of ICD shocks, as well as heart failure hospitalization and cardiovascular hospitalization.

Study context

Population
Patients with an ICD in phase A of the PARTITA studyphase A of PARTITA
Participants
517 patients
Comparison
Active arrhythmia pattern vs no antitachycardia pacing (ATPs)
Primary endpoint
ICD shocks
Methodological detailsclassification and regression tree analysis
  • Classification and regression tree analysis

Primary result

As reported in the abstract

Risk of ICD shocks

Training sample

Testing sample

Secondary outcomes

OutcomeHR (95% CI)P value
Worsening HF5.45 (1.62–18.4)P = 0.006
CV hospitalization7.29 (3.66–14.5)P < 0.001

Original publication

Active Arrhythmia Pattern: A Novel Predictor of ICD Shocks—A Subanalysis From the PARTITA Study. Circ Arrhythm Electrophysiol. Published 1 May 2024. doi:10.1161/circep.123.012523

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