Arrhythmias & electrophysiology
Active Arrhythmia Pattern: A Novel Predictor of Implantable Cardioverter Defibrillator (ICD) Shocks—A Subanalysis From the PARTITA Study
Authors' conclusion
Patients with an active arrhythmia pattern (≥5 ATPs in 6 months) are associated with an increased risk of ICD shocks, as well as heart failure hospitalization and cardiovascular hospitalization.
Study context
- Population
- Patients with an ICD in phase A of the PARTITA studyphase A of PARTITA
- Participants
- 517 patients
- Comparison
- Active arrhythmia pattern vs no antitachycardia pacing (ATPs)
- Primary endpoint
- ICD shocks
Methodological detailsclassification and regression tree analysis
- Classification and regression tree analysis
Primary result
As reported in the abstract
Risk of ICD shocks
Training sample
Testing sample
Secondary outcomes
| Outcome | HR (95% CI) | P value | |
|---|---|---|---|
| Worsening HF | 5.45 (1.62–18.4) | P = 0.006 | |
| CV hospitalization | 7.29 (3.66–14.5) | P < 0.001 | |
| 0.050.21520Hazard ratio (log scale) |
Original publication
Active Arrhythmia Pattern: A Novel Predictor of ICD Shocks—A Subanalysis From the PARTITA Study. Circ Arrhythm Electrophysiol. Published 1 May 2024. doi:10. 1161/ circep. 123. 012523
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