Acute cardiac care & resuscitation
Acute Kidney Injury and Cardiogenic Shock Severity for Mortality Risk Stratification in Patients Supported with VA ECMO
Authors' conclusion
AKI stage, as an index of organ perfusion combined with shock severity measured by the SCAI shock classification, demonstrates a good correlation with in-hospital mortality.
Study context
- Population
- Adults with cardiogenic shock supported with VA ECMO (88.4% postcardiotomy), January 2018 to December 2020
- Participants
- 216 adults
- Exposure
- Acute kidney injury (AKI) stage combined with Society for Cardiovascular Angiography and Interventions (SCAI) shock stage for mortality risk stratification
- Outcome
- In-hospital mortality
Methodological detailssingle-centre, consecutive patients
- Single-centre
- Consecutive patients
Main finding
As reported in the abstract
In-hospital mortality by AKI stage
In-hospital mortality by AKI stage
Prevalence
- Mortality across AKI stages
- P < 0.001
- Total in-hospital mortality
- 53.2%
- AKI occurrence
- 182 (84.3%)
Observational data: associations, not effects.
Further findings
Independent predictors of in-hospital mortality
- AKI stage
- P < 0.001
- SCAI shock stage before ECMO
- P = 0.008
- NYHA ≥ Class III on admission
- P = 0.044
AUC for in-hospital mortality
- AKI stage + SCAI shock stage
- 0.754 (95% CI 0.690 to 0.811)
- AKI stage
- 0.676
- SCAI shock stage
- 0.657
- Serum lactate
- 0.682
- SOFA score
- 0.644
- SVAE score
- 0.582
- VIS score
- 0.530
- Predictors measured prior to ECMO
Original publication
Acute Kidney Injury and Cardiogenic Shock Severity for Mortality Risk Stratification in Patients Supported with VA ECMO. ESC Heart Fail. Published 21 July 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →