Arrhythmias & electrophysiology

Acute post-procedural inducibility is a poor predictor of clinical outcomes in high-risk patients (PAINESD > 17) undergoing scar-related ventricular tachycardia ablation

EuropacePublished Retrospective cohort study

Authors' conclusion

The results of post-ablation PVS do not significantly correlate with long-term outcomes in high-risk (PAINESD > 17) VT ablation patients.

Study context

Population
High-risk patients (PAINESD > 17) undergoing scar-related ventricular tachycardia (VT) ablation, July 2010–July 2022of 1677 VT ablation cases
Participants
123 patients
Exposure
Post-ablation programmed ventricular stimulation (PVS) response: Group A vs Group C
  • Group Bn = 13
Outcome
Composite of:
  • Death
  • Durable LV assist device placement
  • Cardiac transplant
Follow-up
Median 19 months (IQR 4-43 months)
Methodological detailssingle-centre
  • Single-centre

Main finding

As reported in the abstract

Composite of:
  • Death
  • Durable LVAD placement
  • Cardiac transplant
· median follow-up 19 months (IQR 4-43)

Patients with the composite primary endpoint (all groups)

82

66.7%

No difference between Groups A and C: HR 1.21 (0.94-1.57)

P = 0.145

Observational data: associations, not effects.

Secondary outcomes

VT recurrence

No difference between Groups A and C: HR 1.18 (0.91-1.54)
P = 0.210
  • Competing risk analysis
  • Persisted after multivariate adjustments

Original publication

Acute post-procedural inducibility is a poor predictor of clinical outcomes in high-risk patients (PAINESD > 17) undergoing scar-related ventricular tachycardia ablation. Europace. Published 20 July 2024. doi:10.1093/europace/euae185

Summarised from the published abstract; every number is checked against it

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