Arrhythmias & electrophysiology
Substrate Mapping Alters Ventricular Tachycardia Inducibility
Authors' conclusion
Mechanical effects of substrate mapping commonly alter inducibility of VT.
Study context
- Population
- Patients with LV scar-related ventricular tachycardia (VT) inducible by programmed electrical stimulation (PES) undergoing ablation
- Participants
- 28 patients
- Exposure
- Repeat PES after substrate mapping vs after time under sedation/anaesthesia without substrate mapping
- Group In = 14
- Group IIn = 14reference
- Outcome
- Response to second PES: type I same VT induced, type II different VT induced, type III VT not inducible
Main finding
As reported in the abstract
Response to second PES
| Group | Same VT | Different VT | No VT |
|---|---|---|---|
| Group I | 3 (21%) | 9 (64%) | 2 (14%) |
| Group II | 10 (71%) | 3 (21%) | 1 (7%) |
Same VT
Group I3 (21%)
Group II10 (71%)
Different VT
Group I9 (64%)
Group II3 (21%)
No VT
Group I2 (14%)
Group II1 (7%)
- Group I vs Group II: P = 0.017 — distribution of response types
Observational data: associations, not effects.
Further findings
Initial VT cycle length
P = 0.016
| Outcome | Group I | Group II | P value |
|---|---|---|---|
| Extrastimuli required to induce VT in PES 1More extrastimuli in Group I | 2 (range 1–4) | 2 (range 1–3) | P = 0.022 |
Age, time between PES, cardiomyopathy type, EF, anaesthesia methods
- Not different between the 2 groups
Original publication
Substrate Mapping Alters Ventricular Tachycardia Inducibility. Circ Arrhythm Electrophysiol. Published 5 January 2023. doi:10.
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