Arrhythmias & electrophysiology

An individualized criterion for left bundle branch capture in patients with a narrow QRS complex

Heart RhythmPublished Diagnostic accuracy study

Authors' conclusion

ΔV6RWPT could be an accurate individualized criterion for determining LBB capture with high sensitivity and specificity and was superior over the fixed Paced-V6RWPT criterion.

Study context

Population
Patients with a narrow QRS complex in whom both LBBP and LV septal pacing were acquired during operation
Participants
71 patients
Comparison
ΔV6RWPT criterion vs fixed Paced-V6RWPT criterion for left bundle branch (LBB) capture
Outcome
Accuracy of ΔV6RWPT criterion for determining LBBP

Performance

As reported in the abstract

Determination of LBBP
Test or modelSensitivitySpecificityOptimal cutoff
ΔV6RWPT <30 ms100%100%
Paced-V6RWPT84.5%97.2%64.2 ms

Sensitivity

ΔV6RWPT <30 ms100%
Paced-V6RWPT84.5%

Specificity

ΔV6RWPT <30 ms100%
Paced-V6RWPT97.2%

Optimal cutoff

ΔV6RWPT <30 ms— not stated in the abstract
Paced-V6RWPT64.2 ms

Further findings

OutcomeLBBPLVSP
ΔV6RWPT during LBBP vs LVSP21.3 (SD 4.6) ms38.5 (SD 4.6) ms
Range9.3-28.3 ms31.1-47.0 ms

ΔV6RWPT during LBBP vs LVSP

Probability distribution of ΔV6RWPT well separated between LBBP and LVSP

Paced-V6RWPT during LBBP vs LBBpo-V6RWPT

Paced-V6RWPT during LBBP equivalent to LBBpo-V6RWPT in all patients

Correlation of Native-V6RWPT with LBBpo-V6RWPT

Strong linear correlation
r = 0.796; P <.001

Original publication

An individualized criterion for left bundle branch capture in patients with a narrow QRS complex. Heart Rhythm. Published 10 November 2023. doi:10.1016/j.hrthm.2023.11.003

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