Associations of Dietary Calcium and Phosphorus With Vascular and Valvular Calcification: The ARIC Study
Main finding · Coronary artery calcification (Agatston score ≥75th percentile), calcium intakeResult — go to the resultAdjusted odds ratio 0.66 95% CI 0.45–0.98Authors' conclusion
Dietary calcium and phosphorus intakes at middle age were not positively associated with vascular and valvular calcification at over 75 years old.
Study context
- Population
- ARIC participants without CHD (mean age 80.5 years) with chest CT at visit 7 (2018–2019) and FFQ at visits 1 and 3
- Participants
- 1,914 participants
- Exposure
- Highest vs lowest quartile of dietary calcium and phosphorus intake in middle age
- Outcome
- Coronary artery and extra-coronary calcification (Agatston score in coronary artery, ascending and descending aorta, aortic valve ring, aortic valve, mitral valve)
- Follow-up
- Visit 7 (2018-2019)
Main finding
As reported in the abstract
Coronary artery calcification (Agatston score ≥75th percentile), calcium intake
Adjusted odds ratio
0.66
95% CI 0.45–0.98
Highest quartilevs Lowest quartile
adjusted OR 0.66 (95% CI 0.45–0.98)
Observational data: associations, not effects.
Original publication
Associations of Dietary Calcium and Phosphorus With Vascular and Valvular Calcification: The ARIC Study. JACC Adv. Published 20 May 2024. doi:10. 1016/ j. jacadv. 2024. 100993
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