Arrhythmias & electrophysiology
Association of Race and Ethnicity With Stroke and Mortality Outcomes in Atrial Fibrillation
Authors' conclusion
In a nationwide cohort of AF patients, we found significantly higher stroke rates for Black than White patients. Conversely, we observed significantly lower mortality rates for Asian, Black, and Hispanic patients than for White patients. Interventions to address factors associated with these disparities are essential.
Study context
- Population
- Veterans Health Administration patients with incident atrial fibrillation (AF) from January 1, 2014, to December 31, 2021, with follow-up through May 31, 2022patients with AF, mean age 72.9 ± 10.5 years, 97.8% male and 2.2% female
- Participants
- 157,332 patients
- Exposure
- Stroke and mortality by race and ethnicity for AF patients in the Veterans Health Administration
- Outcome
- Stroke and mortality incidence
Methodological detailsCox proportional hazard models, adjusting for sociodemographic, clinical, and facility factors
- Cox proportional hazard models
- Adjusting for sociodemographic, clinical, and facility factors
Main finding
As reported in the abstract
Each group vs whiteAdjusted hazard ratio (95% CI)
Blackstroke; higher for Black
1.14(1.09–1.20)
Asianmortality; lower for Asian
0.85(0.78–0.93)
Blackmortality; lower for Black
0.92(0.89–0.95)
Hispanicmortality; lower for Hispanic
0.82(0.77–0.87)
- Stroke, overall
- 22,628 (14.7%) patients (46.3 per 1,000 person-years)
- Died, overall
- 52,288 (33.2%) patients (96.1 per 1,000 person-years)
Observational data: associations, not effects.
Original publication
Association of Race and Ethnicity With Stroke and Mortality Outcomes in Atrial Fibrillation. JACC Adv. Published 5 June 2025. doi:10. 1016/ j. jacadv. 2025. 101860
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