Valvular & structural heart disease

Association of right atrial strain and long-term outcome in severe secondary tricuspid regurgitation

HeartPublished Retrospective cohort study

Main finding · All-cause mortalityResult — go to the resultHazard ratio 0.928 95% CI 0.864–0.996

Authors' conclusion

Patients with severe STR presented with significant RA remodelling, and lower RA function, as measured by RASr, was independently associated with all-cause mortality, potentially improving risk stratification in these patients.

Study context

Population
Consecutive patients with first diagnosis of severe secondary tricuspid regurgitation and RASr available
Participants
586 patients
Exposure
RASr ≤13% vs RASr >13%
Outcome
All-cause mortality
Follow-up
Median 6.6 years
Methodological detailssingle-centre
  • Single-centre

Main finding

As reported in the abstract

Hazard ratio

0.928

95% CI 0.864–0.996

P = 0.038

Events by group

RASr per 5% increase
HR 0.928 (95% CI 0.864–0.996); P = 0.038

Per 5% increase, as printed

Observational data: associations, not effects.

Further findings

10-year overall survival, overall population (349 deaths)
40%

Original publication

Association of right atrial strain and long-term outcome in severe secondary tricuspid regurgitation. Heart. Published 30 October 2023. doi:10.1136/heartjnl-2023-323084

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