Atrial and Ventricular Arrhythmia in Adults With Shone Complex: A Single-Center Cohort Study
Authors' conclusion
In adults with SC, atrial arrhythmias occurred in one-third of patients, were associated with more HF hospitalizations, and frequently required rhythm control.
Study context
- Population
- Adults with Shone complex (≥2 of supramitral ring, parachute mitral valve, subvalvular/valvular aortic stenosis (AS), aortic coarctation) seen at Mayo Clinic, January 1999 to March 2020mean age 33 ± 13 years
- Participants
- 73 adults
- Outcome
- Prevalence of sustained AF, atrial flutter and ventricular arrhythmias (VA), and outcomes (HF hospitalization, cardiac transplant, death)
Methodological detailssingle-centre (Mayo Clinic), Kaplan-Meier survival analysis used to calculate occurrence of arrhythmias
- Single-centre (Mayo Clinic)
- Kaplan-Meier survival analysis used to calculate occurrence of arrhythmias
Main finding
As reported in the abstract
Arrhythmia prevalence
Atrial arrhythmias (mean age at diagnosis 34.6 ± 12.7 years)
24 patients
33%
Sustained ventricular arrhythmias (VA)
6 of 73 patients
Sustained VA with EF <40%
4
Observational data: associations, not effects.
Further findings
Characteristics of patients with AF and atrial flutter
- Higher number of surgeries, left atrial size, RV systolic pressure and HF hospitalizations
Rhythm control in patients with atrial arrhythmias
- On antiarrhythmic drugs
- 75%
- Underwent catheter ablation
- 50%
Death and cardiac transplantation · median follow-up 7.3 ± 6.0 years
- Death
- 11
- Cardiac transplantation
- 3
Original publication
Atrial and Ventricular Arrhythmia in Adults With Shone Complex: A Single-Center Cohort Study. JACC Adv. Published 7 December 2023. doi:10.
Summarised from the published abstract; every number is checked against it