Valvular & structural heart diseaseCohort study
Balloon-Assisted Translocation of the Mitral Anterior Leaflet to Prevent Outflow Tract Obstruction During Transcatheter Mitral Valve Replacement (TMVR)
- Multicentre cohort study
- international
- consecutive patients
- 22 centres in North America and Europe
Authors' conclusion
BATMAN was associated with high technical success and effectiveness in preventing LVOT obstruction and appeared to be safe in ViR and ViV procedures. Adverse events were higher in ViMAC.
Study context
- Population
- Patients at high risk for left ventricular outflow tract (LVOT) obstruction undergoing transseptal BATMAN TMVR
- Participants
- 83 patients
- Exposure
- BATMAN during transseptal TMVR
- Valve-in-valve (ViV)n = 24
- Valve-in-ring (ViR)n = 39
- Valve-in-mitral annular calcification (ViMAC)n = 19
- Outcome
- Successful TMVR free from LVOT obstruction and procedural death (efficacy); in-hospital death, stroke or major cardiac structural complications (safety)
Main finding
As reported in the abstract
Primary efficacy endpoint
- Primary efficacy endpoint met, overall
- 95.1%
Observational data: associations, not effects.
Further findings
Technical success
- Technical success in all but 1 case (converted to tip-to-base LAMPOON)
- 98.8%
Pre-emptive mechanical cardiocirculatory support
- Used in cases
- 28.9%
Safety
Primary safety endpoint (in-hospital death, stroke or major cardiac structural complications)
| Outcome | ViV | ViR | ViMAC |
|---|---|---|---|
| Major cardiac structural complication attributed to BATMAN | Not reported in the abstract | Not reported in the abstract | 1 events |
- Primary safety endpoint (in-hospital death, stroke or major cardiac structural complications) — Primary safety endpoint, overall
- 7.3%
- Primary safety endpoint (in-hospital death, stroke or major cardiac structural complications): across groups P = 0.02
Original publication
Balloon-Assisted Translocation of the Mitral Anterior Leaflet to Prevent Outflow Tract Obstruction During TMVR. JACC Cardiovasc Interv. Published 20 May 2026. doi:10.1016/j.jcin.2026.04.013
Summarised from the published abstract; every number is checked against it