Acute cardiac care & resuscitation
Blood Perfusion Status is Important in the Prognosis of Ventricular Aneurysm Complicated by Ventricular Septal Rupture
Authors' conclusion
The long-term prognosis of LVA combined with VSR was not inferior than LVA alone after surgery, but poor blood perfusion status was associated with a worse prognosis.
Study context
- Population
- Patients with LV aneurysm (with or without relatively stable ventricular septal rupture (VSR)) undergoing surgerypropensity-score matched
- Participants
- 68 vs 136
- Exposure
- Left ventricular aneurysm (LVA) with VSR vs LVA alone
- LVA and VSRn = 68
- LVA alonen = 136reference
- Outcome
- MACCE:
- Mortality
- MI
- Revascularization
- Stroke
- HF
- Follow-up
- Median 63 months
Methodological detailspropensity-score matched
- Propensity-score matched
Main finding
As reported in the abstract
- No significant difference in primary endpoint between LVA and VSR and LVA alone (log-rank)
- P = 0.63
Observational data: associations, not effects.
Further findings
NYHA IV at admission
P < 0.001
Pre-operative IABP use
P < 0.001
Post-operative IABP use
P < 0.001
- Long-term prognosis by pre-operative intra-aortic balloon pump (IABP) (LVA and VSR subgroup) — Worse long-term prognosis with pre-operative IABP (log-rank)
- P = 0.0011
- Long-term prognosis by pre-operative IABP (LVA and VSR subgroup): Pre-operative IABP n = 23
- Long-term prognosis by pre-operative IABP (LVA and VSR subgroup): Non-pre-operative IABP n = 45
Original publication
Blood Perfusion Status is Important in the Prognosis of Ventricular Aneurysm Complicated by Ventricular Septal Rupture. ESC Heart Fail. Published 28 February 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →