Acute cardiac care & resuscitation
Outcomes with mechanical circulatory support devices among patients with mechanical complications of acute myocardial infarction
Authors' conclusion
In this large observational analysis of AMI hospitalizations, mechanical complications were rare and associated with very high in-hospital mortality. Although the use of MCS has increased, in-hospital mortality rates remain high even among patients who received MCS. Further investigations are needed to clarify the role of MCS devices among patients with mechanical complications of AMI.
Study context
- Population
- AMI admissions (ST-elevation and non-ST-elevation myocardial infarction) with mechanical complications (ventricular septal defect, free wall rupture, or papillary muscle rupture)(0.2%) of 4,450,219 AMI patients had a mechanical complication
- Participants
- 7,025 admissions
- Exposure
- Those who received mechanical circulatory support (MCS) vs. those who did not
- Those who received MCSn = 3,115
- Outcome
- MCS use trend
- Follow-up
- 2016 to 2020
Methodological detailsNational Inpatient Sample, years 2016-20
- National Inpatient Sample
- Years 2016-20
Main finding
As reported in the abstract
MCS use in 2016
39.3%
MCS use in 2020
48.9%
Observational data: associations, not effects.
Further findings
In-hospital mortality
In-hospital mortality trend · 2016 vs. 2020
- In-hospital mortality in 2016
- 36.9%
- In-hospital mortality in 2020
- 43.4%
- Ptrend = 0.75
In-hospital mortality
- There was no significant difference in in-hospital mortality
Original publication
Outcomes with mechanical circulatory support devices among patients with mechanical complications of acute myocardial infarction. Eur Heart J Acute Cardiovasc Care. Published 14 March 2025. doi:10.
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