Brief Mindfulness-Based Cognitive Therapy in Women With Myocardial Infarction: Results of a Multicenter Randomized Controlled Trial
Authors' conclusion
MBCT-Brief was associated with greater 6-month reductions in stress than an active control among adherent participants. More frequent mindfulness practice was associated with greater improvements in psychological outcomes. Strategies to engage women with MI in mindfulness training and support regular home practice may enhance these effects.
Study context
- Population
- Women with elevated stress (Perceived Stress Scale [PSS-4]≥6) at least 2 months after myocardial infarction (MI)women with MI (mean age 59.8 ± 12.8 years, 34% racial/ethnic minorities)
- Participants
- 130 women
- Comparison
- Remotely delivered mindfulness intervention vs heart disease education
- Primary endpoint
- Changes in stress (PSS-10)
- Follow-up
- 6 months
Methodological details12 hospitals in the United States and Canada and via community advertising, remotely delivered
- 12 hospitals in the United States and Canada and via community advertising
- Remotely delivered
Primary result
As reported in the abstract
MBCT-Brief
−0.52
change · 95% CI −0.77–-0.28
Heart disease education
−0.19
change · 95% CI −0.45–0.06
MBCT-Brief vs heart disease education: P = 0.070 · MBCT-Brief vs heart disease education: P = 0.049
Secondary outcomes
Secondary outcomes (depressive symptoms, anxiety, quality of life, disease-specific health status, actigraphy-assessed sleep)
- No significant differences in secondary outcomes in intention-to-treat or per-protocol analyses
Mindfulness practice frequency within the MBCT-Brief arm
- Greater reductions in stress
- P = 0.007
- Depressive symptoms
- P = 0.017
- Anxiety
- P = 0.036
- More frequent mindfulness practice was associated with greater reductions
Original publication
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