Prevention & lipids

Cardiac Ventricular Hinge Point Late Gadolinium Enhancement (LGE) Is Highly Prevalent and Sex-Dependent in ELITE Athletes

Circ Cardiovasc ImagingPublished Prospective cohort study

Main finding · HP-LGE prevalenceResult — go to the resultOdds ratio 3.07 95% CI 1.32–7.32

Authors' conclusion

HP-LGE is a common finding in asymptomatic, elite athletes and is strongly associated with sex. Lower left ventricle ejection fraction is moderately associated with HP-LGE.

Study context

Population
Asymptomatic young elite (national-, international-, Olympic- or Paralympic-level) athletes, 40% women, median age 25.1 years40% women
Participants
309 participants
Exposure
Athletes with hinge point LGE (HP-LGE) vs without HP-LGE; men vs women
  • HP-LGEn = 124
Outcome
Prevalence of hinge point LGE on CMR

Main finding

HP-LGE prevalence

Odds ratio

3.07

95% CI 1.32–7.32

P = 0.010

By group

Male sex
OR 3.07 (95% CI 1.32–7.32); P = 0.010

As reported in the abstract

Overall HP-LGE prevalence
124 (40%)

Observational data: associations, not effects.

Further findings

LV end-systolic volume indexed to BSA

P = 0.037

RV end-systolic volume indexed to BSA

P = 0.020

LVEF

P = 0.035

RV EF

P = 0.021

Estimated global LV extracellular volume

P = 0.015

Original publication

Cardiac Ventricular Hinge Point LGE Is Highly Prevalent and Sex-Dependent in ELITE Athletes. Circ Cardiovasc Imaging. Published 8 October 2025. doi:10.1161/circimaging.124.017765

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