Prevention & lipidsCohort study

Cardiovascular disease averted by China’s Clean Air Act and the potential benefit of further air pollution intervention: evidence based on the parametric G-computation

Eur J Prev CardiolPublished

  • Prospective cohort study with parametric G-computation simulation
  • Parametric G-formula

Authors' conclusion

Existing air pollutant intervention policies have achieved considerable public health benefits in reducing CVD risk, and there is still significant room for improvement.

Study context

Population
China Multi-Ethnic Cohort; exposures PM2.5 and O3
Exposure
China's Clean Air Act (CCAA) and stricter air-pollution interventions vs no CCAA implementation
Outcome
CVD cases averted per 100 000 people and relative risk

Main finding

As reported in the abstract

CVD cases averted per 100 000 people
GroupValueWHO AQG, PM2.5 (95% CI 7,400, 17,405)WHO AQG, O3 (95% CI 1,189, 10,840)WHO AQG, joint pollutants (95% CI 10,148, 17,998)
CCAA benefit evaluation541 (95% CI 184–914) per 100 000 people
Threshold intervention13 530649815 449

Observational data: associations, not effects.

Original publication

Cardiovascular disease averted by China’s Clean Air Act and the potential benefit of further air pollution intervention: evidence based on the parametric G-computation. Eur J Prev Cardiol. Published 23 January 2026. doi:10.1093/eurjpc/zwag039

Summarised from the published abstract; every number is checked against it