Cardiovascular disease burden and risk factor management in cancer survivors: insights into a multiethnic, socioeconomically deprived urban population
Authors' conclusion
Cancer survivors have an elevated risk of CVD, with variations by cancer type and ethnicity.
Study context
- Population
- Multiethnic, socioeconomically deprived urban primary care populationmatched cohort
- Exposure
- Cancer survivors vs non-cancer comparators
- Cancer survivorsn = 18,839
- Outcome
- CVD prevalence and risk factor control (BP, cholesterol, statin prescriptions)
Methodological detailselectronic health records, 127 urban primary care practices, multivariable regression
- Electronic health records
- 127 urban primary care practices
- Multivariable regression
Main finding
As reported in the abstract
CVD in cancer survivors vs non-cancer comparators, by cancer type
Odds ratio (95% CI)
HaematologicalHF;vs non-cancer comparators
2.12(1.44–3.09)
Breast cancer survivorsHF;vs non-cancer comparators
1.38(1.16–1.64)
Bladderischaemic heart disease;vs non-cancer comparators
1.50(1.20–1.87)
Lung cancerischaemic heart disease;vs non-cancer comparators
1.44(1.09–1.87)
Ovarian cancerVTE;vs non-cancer comparators
5.72(3.54–9.32)
Cancer survivors vs Non-cancer comparatorsBP control slightly better;vs non-cancer comparators
0.92(0.87–0.97)
Observational data: associations, not effects.
Further findings
| Outcome | OR (95% CI) | |
|---|---|---|
| BP controlSlightly better in cancer survivors | 0.92 (0.87–0.97) | |
| 0.512Odds ratio (log scale) |
BP control
- One in three patients did not meet guideline-directed targets
Statin use and cholesterol management
- Similar between survivors and controls; disparities within certain ethnic groups
Original publication
Cardiovascular disease burden and risk factor management in cancer survivors: insights into a multiethnic, socioeconomically deprived urban population. Heart. Published 13 March 2025. doi:10. 1136/ heartjnl-2024-325309
Composed by AI from the published abstract and checked against it. How Briefs are made →