Arrhythmias & electrophysiology

Catheter ablation of intramural outflow tract premature ventricular complexes: a multicentre study

EuropacePublished Multicentre case series

Authors' conclusion

Ablation of intramural PVCs is challenging; acute arrhythmia elimination is achieved in 3/4 patients, and non-conventional approaches are often necessary for success.

Study context

Population
Patients with structurally normal heart or nonischemic cardiomyopathy and intramural outflow tract premature ventricular complexes (PVCs)26 with previous ablations
Participants
92 patients
Outcome
Acute and long-term outcomes of ablation

Main finding

As reported in the abstract

Acute PVC suppression
75%
PVC burden before ablation (mean)
21.5±10.9%
PVC burden after procedure (mean)
5.8±8.4%
Repeat ablation during follow-up
16 patients
Mean follow-up
15±14 months

Observational data: associations, not effects.

Further findings

Mapping and ablation techniques

Direct intramural septal mapping
29 patients (32%)
Earliest activation within septal vein (of directly mapped)
13
Sequential unipolar ablation
73%
Low-ionic irrigation
26%
Bipolar ablation
15%
Ethanol ablation
1%
LBBB pattern
68%

Original publication

Catheter ablation of intramural outflow tract premature ventricular complexes: a multicentre study. Europace. Published 25 April 2023. doi:10.1093/europace/euad100

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