Changes in Physical Activity and Cardiovascular Disease Risk in Cancer Survivors: A Nationwide Cohort Study
Authors' conclusion
These findings underscore the importance of maintaining physical activity for cardiovascular health in cancer survivors and suggest that physical activity before a diagnosis may offer enduring protection against ischemic heart disease and cardiac dysfunction.
Study context
- Population
- Cancer survivors (mean age 56.3, 45.7% men); physical activity assessed 2 years before and after diagnosis
- Participants
- 269,943 survivors
- Exposure
- Physical activity patterns before and after cancer diagnosis vs remaining inactive
- Outcome
- Incidence of myocardial infarction (MI), heart failure (HF) and atrial fibrillation
Methodological detailsnationwide
- Nationwide
Main finding
As reported in the abstract
Each group vs remained inactiveSubdistribution hazard ratio (95% CI)
Persistent physical activityMI
0.80(0.70–0.91)
Persistent physical activityHF
0.84(0.78–0.90)
Initiating physical activityMI
0.89(0.79–0.99)
Initiating physical activityHF
0.87(0.82–0.93)
Active only before diagnosisMI
0.80(0.71–0.91)
Active only before diagnosisHF
0.94(0.88–1.00)
Observational data: associations, not effects.
Further findings
- Associations varied by primary cancer site
Original publication
Changes in Physical Activity and Cardiovascular Disease Risk in Cancer Survivors: A Nationwide Cohort Study. JACC CardioOncol. Published 3 December 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →