Arrhythmias & electrophysiology

Clinical characteristics of electrical storm in patients with early repolarization syndrome

Heart RhythmPublished Cohort study

Authors' conclusion

Patients with ERS in the ES group frequently had short QT and QTp intervals, pilsicainide-induced ST elevations, and high Shanghai Score System scores. Therapeutic hypothermia was also associated with acute phase ES.

Study context

Population
Patients with early repolarization syndrome (ERS) who experienced ventricular fibrillation (VF)/SCD or arrhythmic syncope
Participants
44 patients
Exposure
Electrical storm (ES) vs no ES
  • ESn = 13
Outcome
Electrical storm and its risk factors

Main finding

As reported in the abstract

Electrical storm

Patients experiencing ES

13

30%

ES during acute phase of initial VF episodes

11

85%

ES during follow-up

2

2%

VF with ES during therapeutic hypothermia

6 of 13

46%

Observational data: associations, not effects.

Further findings

J-wave voltage during therapeutic hypothermia

Higher in ES than without ES

Isoproterenol use

Used in 5 patients (38%); decreased J-wave voltage and relieved ES
5 (38%)

Pilsicainide-induced ST elevation; spontaneous Brugada ECG pattern

Pilsicainide induced ST elevation
6 of 34 (18%)
Spontaneous Brugada ECG patterns did not appear associated with VF

Original publication

Clinical characteristics of electrical storm in patients with early repolarization syndrome. Heart Rhythm. Published 17 January 2024. doi:10.1016/j.hrthm.2024.01.016

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