Valvular & structural heart disease

Clinical Presentation and Outcomes After Surgery for Mitral Regurgitation: Real-World Insights From the MITRACURE International Registry

CirculationPublished Retrospective cohort study

Authors' conclusion

Patients were often referred late in the disease process, with few patients undergoing early intervention.

Study context

Population
Consecutive adults undergoing isolated or combined mitral valve surgery for mitral regurgitation (MR) in France or Canada in 2019
Participants
3,522 adults40 centres
Outcome
Repair rate and in-hospital mortality after MVS for MR
Follow-up
In-hospital
Methodological detailsinternational registry, multicentre, consecutive patients
  • International registry
  • Multicentre
  • Consecutive patients

Main finding

As reported in the abstract

in-hospital
Repair rate, overall
62%
Repair rate, myxomatous disease
80%
In-hospital mortality, overall
4.5%
In-hospital mortality, myxomatous MR
2.3%
In-hospital mortality, myxomatous MR, isolated mitral valve surgery (MVS)
1.8%
In-hospital mortality, myxomatous MR, combined MVS
3.1%

Observational data: associations, not effects.

Original publication

Clinical Presentation and Outcomes After Surgery for Mitral Regurgitation: Real-World Insights From the MITRACURE International Registry. Circulation. Published 31 August 2025. doi:10.1161/circulationaha.124.073674

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