Arrhythmias & electrophysiology
Comparison of excess mortality between atrial fibrillation, heart failure, myocardial infarction, and stroke: trends over 2000–22
Authors' conclusion
AF was the condition or was among those with the smallest improvement in relative survival and AF and stroke showed the smallest improvement in 1-year excess mortality.
Study context
- Population
- All individuals newly diagnosed with atrial fibrillation (AF), heart failure (HF), myocardial infarction (MI) or stroke in Denmark, 2000–2021
- Exposure
- AF vs HF, MI and stroke
- AFn = 364,199
- HFn = 242,570
- MIn = 172,552
- Stroken = 281,407
- Outcome
- Trends in relative survival and excess mortality rates vs general population (adjusted for age, sex, calendar year)
- Follow-up
- 1, 5 and 10 years after diagnosis
Methodological detailsgeneral Danish population as comparator
- General Danish population as comparator
Main finding
As reported in the abstract
Average improvement in relative survival over calendar years
- AF smallest average improvement at 1 year (per year)
- 0.35%
- AF smallest average improvement at 5 years (per year)
- 0.58%
- 10 years: AF average improvement (per year; AF, MI, stroke smallest)
- 0.77%
- 10 years: MI average improvement (per year)
- 0.72%
- 10 years: stroke average improvement (per year)
- 0.80%
Observational data: associations, not effects.
Further findings
Average improvement in excess mortality rate over calendar years
- 1 year: AF (smallest, with stroke), additional deaths per 1000 person-years per year
- −1.02
- 1 year: stroke, additional deaths per 1000 person-years per year
- −0.96
- 5 years: MI smallest, additional deaths per 1000 person-years per year
- −0.13
- No average improvement in 10-year excess mortality rate for MI
Original publication
Comparison of excess mortality between atrial fibrillation, heart failure, myocardial infarction, and stroke: trends over 2000–22. Eur J Prev Cardiol. Published 25 June 2025. doi:10. 1093/ eurjpc/ zwaf371
Composed by AI from the published abstract and checked against it. How Briefs are made →