Arrhythmias & electrophysiology

Comparison of strategies for catheter ablation of left posterior fascicular ventricular tachycardia

EuropacePublished Cohort study

Authors' conclusion

Left posterior fascicular-ventricular tachycardia ablation utilizing FAP and traditional ablation approaches resulted in similar acute and long-term procedural outcomes. Serious His-Purkinje injury did occur infrequently during traditional ablation. The use of FAP ablation approach was associated with shorter procedure time and fewer radiofrequency energy applications, especially for non-inducible patients.

Study context

Population
Consecutive patients with ECG-documented left posterior fascicular ventricular tachycardia (VT) referred for catheter ablation
Participants
189 patients
Exposure
Fragmented antegrade Purkinje (FAP) ablation vs traditional ablation
  • FAPn = 95
  • Traditionaln = 94reference
Outcome
Freedom from recurrent VT off antiarrhythmic drugs
Follow-up
Mean 65 months
Methodological detailsconsecutive patients
  • Consecutive patients

Main finding

As reported in the abstract

P = 0.157

Observational data: associations, not effects.

Further findings

Procedure time

P = 0.03

OutcomeFAPTraditionalP value
Radiofrequency energy applications4.1 ± 2.46.3 ± 3.5P = 0.003
Freedom from recurrent VT off antiarrhythmic drugs · mean follow-up 65 months
P = 0.157

Safety

Left posterior fascicular block

P < 0.001

Complete AV block and left bundle branch block

Complete AV block in Traditional
1
Left bundle branch block in Traditional
1

Original publication

Comparison of strategies for catheter ablation of left posterior fascicular ventricular tachycardia. Europace. Published 16 November 2023. doi:10.1093/europace/euad339

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