Coronary disease & ACS

Coronary Heart Disease Attributable to Psychosocial Stressors at Work

JACC AdvPublished Prospective cohort study

Authors' conclusion

In this cohort, combined exposure to job strain and ERI accounted for approximately one-fifth of CHD events.

Study context

Population
Employees of public and semipublic organizations in Quebec City, Canada, without CVD at baseline, followed 2004–2018
Participants
6,295 employees
Exposure
Psychosocial stressors at work and coronary heart disease (CHD)
Outcome
Fraction of CHD events attributable to psychosocial stressors at work
Follow-up
15-year follow-up
Methodological detailsmultiple imputation, inverse probability weighting, first 5 years of follow-up excluded
  • Multiple imputation
  • Inverse probability weighting
  • First 5 years of follow-up excluded

Main finding

As reported in the abstract

Attributable fraction for CHD

Observational data: associations, not effects.

Further findings

CHD incidence (whole cohort) · 15-year follow-up

CHD events
669
Person-years
112,297
CHD incidence rate
5.96 per 1,000 person-years

Original publication

Coronary Heart Disease Attributable to Psychosocial Stressors at Work. JACC Adv. Published 19 September 2025. doi:10.1016/j.jacadv.2025.102160

Composed by AI from the published abstract and checked against it. How Briefs are made →

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