Acute cardiac care & resuscitation
Current spectrum and outcomes of infarct-related cardiogenic shock: insights from the CULPRIT-SHOCK registry and randomized controlled trial
Authors' conclusion
In specialized centres in Europe, short- and long-term mortality of patients with infarct-related CS treated with an invasive strategy is still high and mainly depends on the extent of CAD.
Study context
- Population
- Consecutive patients with acute MI complicated by cardiogenic shock screened for CULPRIT-SHOCK (RCT and accompanying registry)369 in registry
- Participants
- 1,075 patients
- Primary endpoint
- Total mortality
- Follow-up
- 30 days and 1 year
Methodological details83 specialized centres in Europe, 1-year follow-up
- 83 specialized centres in Europe
- 1-year follow-up
Primary result
As reported in the abstract
Total mortality at 30 days
47.6%
Total mortality at 1 year
52.9%
Further findings
1-year mortality by extent of coronary artery disease (CAD)
- Left main (LM) coronary artery stenosis
- 63.5%
- Three-vessel CAD
- 56.6%
- Two-vessel CAD
- 49.8%
- One-vessel CAD
- 38.6%
Mechanical complications
- Mechanical complications
- 21/1008; 2.1%
- 1-year mortality with mechanical complications
- 66.7%
Thrombolysis in myocardial infarction (TIMI) 3 patency of infarct vessel after PCI
- TIMI 3 patency after PCI
- 83.6%
Original publication
Current spectrum and outcomes of infarct-related cardiogenic shock: insights from the CULPRIT-SHOCK registry and randomized controlled trial. Eur Heart J Acute Cardiovasc Care. Published 13 February 2024. doi:10.
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