Acute cardiac care & resuscitation

Decoding Cardiogenic Shock: Assessing Shock Index and Its Variants as Prognostic Indicators for In-Hospital Mortality

ESC Heart FailPublished Retrospective cohort study

Authors' conclusion

Shock index and its variants, especially ASI, AMSI, and SIC, may be helpful in predicting in-hospital mortality in CS patients.

Study context

Population
Patients with cardiogenic shock866 (67.6%) survived to discharge
Participants
1,282 patients
Exposure
Shock index (SI) and its variants as prognostic indicators of in-hospital mortality
Outcome
Predictive accuracy (ROC AUC) of shock indices for in-hospital mortality
Follow-up
In-hospital

Main finding

As reported in the abstract

In-hospital mortality prediction
GroupAUC
Adjusted shock index (ASI)0.654
Age-modified shock index (AMSI)0.667
Shock index-C (SIC)0.659

AUC

Adjusted shock index (ASI)0.654
Age-modified shock index (AMSI)0.667
Shock index-C (SIC)0.659

Observational data: associations, not effects.

Further findings

OutcomeASIAMSISIC
In-hospital mortality prediction, STEMI and ACS (subgroups)
AUC, STEMI— not stated in the abstract— not stated in the abstract0.714
AUC, ACS— not stated in the abstract— not stated in the abstract0.696
In-hospital mortality prediction, OHCA (subgroup)
AUC0.7010.707— not stated in the abstract

— not stated in the abstract

Baseline characteristics, non-survivors vs survivors

Age, non-survivors vs survivors
66.0 ± 13.7 vs. 57.4 ± 16.2, P < 0.001
ACS presentation
33.4% vs. 16.1%, P < 0.001
OHCA presentation
11.3% vs. 5.3%, P < 0.001

Original publication

Decoding Cardiogenic Shock: Assessing Shock Index and Its Variants as Prognostic Indicators for In-Hospital Mortality. ESC Heart Fail. Published 6 June 2024. doi:10.1002/ehf2.14853

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