Arrhythmias & electrophysiologyCohort study
Diagnostic Impact and Prognostic Value of Cardiac Magnetic Resonance in Patients With Ventricular Arrhythmias
- Prospective cohort study
- consecutive patients
Authors' conclusion
In patients presenting with ventricular arrhythmias, multiparametric CMR assessment provides diagnostic clarification and effective risk stratification beyond current standard of care.
Study context
- Population
- Consecutive patients undergoing cardiac magnetic resonance (CMR) for assessment of ventricular arrhythmias
- Participants
- 642 patients
- Exposure
- Abnormal vs normal CMR in patients with nonsustained ventricular tachycardia (NSVT) or sustained ventricular tachycardia (VT)/aborted sudden cardiac death (SCD)
- NSVTn = 345
- VT/SCDn = 297
- Outcome
- MACE:
- Death
- Recurrent VT/VF requiring therapy
- Hospitalization for congestive HF
- Follow-up
- Median 4.4 years
Main finding
As reported in the abstract
MACE
Abnormal CMR vs Normal CMRHazard ratio (95% CI)P value
NSVT; multivariate model including LVEF
5.23(2.28–12.0)
P < 0.001VT/SCD; multivariate model including LVEF
1.88(1.07–3.30)
P = 0.03Observational data: associations, not effects.
Further findings
Structurally abnormal heart by CMR
Diagnostic change after CMR
- Structurally abnormal heart by CMR: P < 0.001
- Diagnostic change after CMR: P < 0.001
Incremental value of CMR in major adverse cardiac events (MACE) model (NSVT)
- Significant improvement in integrated discrimination improvement and improvement in C-statistic in NSVT cohort
Original publication
Diagnostic Impact and Prognostic Value of Cardiac Magnetic Resonance in Patients With Ventricular Arrhythmias. JACC Cardiovasc Imaging. Published 14 June 2023. doi:10.1016/j.jcmg.2023.04.008
Summarised from the published abstract; every number is checked against it