Valvular & structural heart disease
Distance between the lead-implanted site and tricuspid valve annulus in patients with left bundle branch pacing: Effects on postoperative tricuspid regurgitation deterioration
Authors' conclusion
TR was a common complication of LBBP implantation. In patients with none/trivial or mild TR, Lead-TA-dist ≤16.1 mm was an independent predictor of TR deterioration after LBBP implantation.
Study context
- Population
- Patients receiving Left Bundle Branch Pacing (LBBP), January 2018 to August 2020
- Participants
- 89 patients
- Exposure
- Tricuspid regurgitation (TR) deterioration vs no TR deterioration after LBBP, by lead position
- Grade 0/1n = 58
- Grade 2/3n = 31
- Outcome
- Incidence of post-LBBP TR deterioration and its predictors (lead position parameters)
- Follow-up
- 19.0 ± 6.5 months
Methodological detailsconsecutive enrolment
- Consecutive enrolment
Main finding
As reported in the abstract
TR deterioration after LBBP · 19.0 ± 6.5 months
TR deterioration, all patients
29
32.6%
TR deterioration in grade 0/1 subgroup
23
Observational data: associations, not effects.
Further findings
Lead-TA-dist ≤16.1 mm and TR deterioration
| HR (95% CI) | P value | ||
|---|---|---|---|
| Lead-TA-dist ≤16.1 mmIndependently associated | 0.20 (0.06–0.76) | P = 0.017 | |
| 0.050.21520Hazard ratio (log scale) |
| Outcome | TR deterioration | No TR deterioration | P value |
|---|---|---|---|
| Lead-TA-dist in grade 0/1 subgroup, TR deterioration vs none | 19.0 (SD 7.6) | 23.9 (SD 5.4) | P = 0.006 |
Lead-TA-dist for predicting TR deterioration (ROC)
- AUC
- 0.721 (95% CI 0.575-0.867; P = .005)
Original publication
Distance between the lead-implanted site and tricuspid valve annulus in patients with left bundle branch pacing: Effects on postoperative tricuspid regurgitation deterioration. Heart Rhythm. Published 5 November 2022. doi:10.
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