Valvular & structural heart disease
Normative values of the aortic valve area and Doppler measurements using two-dimensional transthoracic echocardiography: results from the Multicentre World Alliance of Societies of Echocardiography Study
Authors' conclusion
WASE data provide clinically relevant information about significant differences in normal AVA and Doppler parameters according to sex, age, and race.
Study context
- Population
- Healthy adults, World Alliance Societies of Echocardiography (WASE) Study48% women
- Participants
- 1,903 adults
- Exposure
- Women vs men; by age and race
- Outcome
- Sex-, age- and race-specific normative values for AVA and Doppler parameters
Methodological detailsmulticentre
- Multicentre
Main finding
As reported in the abstract
- Women had smaller left ventricular outflow tract (LVOT) diameters and aortic valve area (AVA), and higher AV peak velocities and mean gradients vs men
- all P < 0.05
- LVOT and AV VTI significantly higher in women; both increased with age in both sexes
- P < 0.05
Observational data: associations, not effects.
Further findings
Women meeting current diagnostic criteria for AS
- Mild AS
- 13.5%
- Moderate AS
- 1.4%
LVOT diameter and AVA by age and race
- Lower in older subjects, both men and women, and lower in Asians vs whites and blacks
Original publication
Normative values of the aortic valve area and Doppler measurements using two-dimensional transthoracic echocardiography: results from the Multicentre World Alliance of Societies of Echocardiography Study. Eur Heart J Cardiovasc Imaging. Published 4 November 2022. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →